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Sialyl Tn or STn (Neu5Acα2-6GalNAcα-O-Thr) at Thr144
Used as a fluorogenic substrate for glycosidases acting on the GAG linkage region or related xylose/glucuronic acid linkages
while the free α-carboxylic acid couples to the resin-bound peptide
STF (Neu5Acα2-3Galβ1-3GalNAcα) at Thr 541
AG152015: β-D-GalNAc-Pentyl-Carboxylic Acid (Peracetate) Pack Size:50 mg Sialyl Tn or STn (Neu5Acα2-6GalNAcα-O-Thr)C20H31NO11 461. 46 A peracetylated D N acetylgalactosamine (GalNAc) ligand equipped with a terminal carboxylic acid through a pentyl spacer, with the sugar hydroxyl groups protected as acetate esters. The peracetate groups increase lipophilicity to facilitate cell membrane permeability. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and reacted with amine functionalized platforms or lysine residues on
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