AG142015: β-D-GalNAc-Butyl-Carboxylic Acid (Peracetate) Pack Size:250 mg Val542 has been labelled with

Val542 has been labelled with d8

Fmoc-Ser(beta-L-Rha(Ac)3)-OH

a protein encoded by the FZD8 gene

32 / A β-D-N-acetylglucosamine (GlcNAcβ) ligand equipped with a terminal carboxylic acid through a short butyl spacer

AG142015: β-D-GalNAc-Butyl-Carboxylic Acid (Peracetate) Pack Size:250 mg Val542 has been labelled withC19H29NO11 447. 43 A peracetylated D N acetylgalactosamine (GalNAc) ligand equipped with a terminal carboxylic acid through a short butyl spacer, with the sugar hydroxyl groups protected as acetate esters. The peracetate groups increase lipophilicity to facilitate cell membrane permeability. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and reacted with amine functionalized platforms or lysine residues on