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Several studies have disclosed important associations between the predisposition of hypersensitivity reactions to some drugs and specific HLA alleles (25), and since some alleles are more frequent in some ethnic groups than in others, these associations appear to be drug-, phenotype- and ethnicity-specific (25)

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Monitoring During Therapy Verify: Consistent suction No air leaks Exudate is entering canister Check : Color of wound edge Level of pain Condition of surrounding skin Dressing Changes 4872 hours for aseptic wounds 24 hours if infected At dressing change: Carefully remove old dressing (moisten if adherent) Inspect for foam crumbs remaining Clean and re-dress with sterile technique Protect Periwound Skin Apply skin barrier film or zinc oxide to avoid maceration or irritation from adhesive

Bake in greased baking dish for about 40 minutes